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Article

Association of testicular germ cell tumor with polymorphisms in estrogen receptor and steroid metabolism genes.

Endocrine-related cancer - 1 Mar 2010

Ferlin Alberto, Ganz Francesco, Pengo Manuel, Selice Riccardo, Frigo Anna Chiara, Foresta Carlo

Abstract excerpt

It is generally assumed that the development of testicular germ cell tumor (TGCT) is under endocrine control. In particular, unbalanced androgen/estrogen levels and/or activity are believed to represent the key events for TGCT development and progression. Furthermore, recent evidence has suggested a strong genetic component for TGCT. In this study, we analyzed whether a genetic variation in estrogen receptor...

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Source

Identifiers

PMID: 19776291
DOI: 10.1677/ERC-09-0176

Genes

COMT
ESR1
ESR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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