Absence of the c-Ha-ras codon 61 point mutation in murine solid tumors induced by subcutaneously applied 7,12-dimethylbenzanthracene.

doi:10.1016/0304-3835(90)90035-v

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Article

Absence of the c-Ha-ras codon 61 point mutation in murine solid tumors induced by subcutaneously applied 7,12-dimethylbenzanthracene.

Cancer letters - 5 Nov 1990

Andrews D F, Collins S J, Reddy A L

Abstract excerpt

The c-Ha-ras-1 codon 61 A----T transversion is a highly consistent finding in murine skin DMBA-initiated/TPA-promoted papillomas and carcinomas. We performed Xba I RFLP analysis on DNA from clonal cell lines derived from 11 independent papillomas and a single carcinoma derived from topically appl...

Topics

9,10-Dimethyl-1,2-benzanthracene
Alleles
Animals
Base Sequence
Codon
Female
Fibrosarcoma
Gene Expression Regulation, Neoplastic
Genes, ras
Heterozygote
Mice
Mice, Inbred BALB C

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Neoplasms, Experimental

Oncogenes

Polymorphism, Restriction Fragment Length

Tetradecanoylphorbol Acetate

Source

Open in PubMed

Identifiers

PMID: 1977513
DOI: 10.1016/0304-3835(90)90035-v

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1977513-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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