Article
Absence of the c-Ha-ras codon 61 point mutation in murine solid tumors induced by subcutaneously applied 7,12-dimethylbenzanthracene.
Cancer letters - 5 Nov 1990
Andrews D F, Collins S J, Reddy A L
Abstract excerpt
The c-Ha-ras-1 codon 61 A----T transversion is a highly consistent finding in murine skin DMBA-initiated/TPA-promoted papillomas and carcinomas. We performed Xba I RFLP analysis on DNA from clonal cell lines derived from 11 independent papillomas and a single carcinoma derived from topically applied DMBA and compared this to RFLP on DNA from 7 clonal fibrosarcoma cell lines derived from tumors arising after...
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