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Article

Analysis of ras gene mutational spectra in epidermal papillomas from K6/ODC transgenic mice.

Molecular carcinogenesis - 1 Jul 1998

Megosh L, Halpern M, Farkash E, O'Brien T G

Abstract excerpt

In standard mouse strains, a high proportion (more than 90%) of epidermal tumors produced by initiation with 7,12-dimethylbenz[a]anthracene and promotion with a variety of chemical agents contain an activating mutation in codon 61 (A182-->T) of the c-Ha-ras gene. We analyzed the ras mutational spectra in 69 tumors induced by DMBA in a unique transgenic model, the K6/ODC mouse. In this model, low-dose DMBA...

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Source

Identifiers

PMID: 9688139
DOI: 10.1002/(sici)1098-2744(199807)22:3<145::aid-mc1>3.0.co;2-k

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Analysis of ras gene mutational spectra in epidermal papillomas from K6/ODC transgenic mice.PMID 9688139Read ↗

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