Article
RRD1, a component of the TORC1 signalling pathway, affects anaesthetic response in Saccharomyces cerevisiae.
Yeast (Chichester, England) - 1 Dec 2009
Palmer Laura K, Baptiste Beverly A, Fester John C, Perkins Justin C, Keil Ralph L
Abstract excerpt
The molecular mechanisms of action of volatile anaesthetics remain unknown despite clinical use for over 150 years. While many effects of these agents have been characterized, clear insight into how these effects relate to the physiological state of anaesthesia has not been established. Volatile anaesthetics arrest cell division in Saccharomyces cerevisiae in a manner that parallels the anaesthetic actions of...
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