Volatile anesthetic additivity and specificity in Saccharomyces cerevisiae: implications for yeast as a model system to study mechanisms of anestheitc action.

doi:10.1097/00000542-199807000-00024

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Article

Volatile anesthetic additivity and specificity in Saccharomyces cerevisiae: implications for yeast as a model system to study mechanisms of anestheitc action.

Anesthesiology - 1 Jul 1998

Wolfe D, Hester P, Keil R L

Abstract excerpt

BACKGROUND: In animals, combinations of volatile anesthetics are additive for inducing anesthesia. Furthermore, although there is a correlation between lipophilicity and anesthetic potency, not all volatile lipophilic compounds are anesthetic. Previously the authors demonstrated the effects of vo...

Topics

Anesthetics, Inhalation
Drug Resistance, Multiple
Isoflurane
Methoxyflurane
Mutation
Saccharomyces cerevisiae

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