Article
Genotype-phenotype analysis of angiotensinogen polymorphisms and essential hypertension: the importance of haplotypes.
Journal of hypertension - 1 Jan 2010
Watkins W Scott, Hunt Steven C, Williams Gordon H, Tolpinrud Whitney, Jeunemaitre Xavier, Lalouel Jean-Marc, Jorde Lynn B
Abstract excerpt
OBJECTIVES: To better understand the relationship between angiotensinogen (AGT) genetic variation and essential hypertension, AGT genotypes and haplotypes were tested for association with hypertensive endophenotypes and essential hypertension. METHODS: Two hundred and fifty-six Hypertensive Pathotype (HyperPATH)/Specialized Center of Research (SCOR) cases and 126 controls were genotyped for 24 single-nucleotide...
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