Article
Renin gene polymorphism: its relationship to hypertension, renin levels and vascular responses.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2011
Sun Bei, Williams Jonathan S, Pojoga Luminita, Chamarthi Bindu, Lasky-Su Jessica, Raby Benjamin A, Hopkins Paul N, Jeunemaitre Xavier, Brown Nancy J, Ferri Claudio, Williams Gordon H
Abstract excerpt
The renin gene has been previously reported to be associated with essential hypertension in a variety of ethnic groups. However, no studies have systematically evaluated the relationship between single nucleotide polymorphisms (SNPs) representing coverage of the entire renin gene and hypertension risk. To evaluate the association between renin gene variation and hypertension we investigated data on HyperPATH...
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