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Article

Hypercontrols in genotype-phenotype analysis reveal ancestral haplotypes associated with essential hypertension.

Hypertension (Dallas, Tex. : 1979) - 1 Apr 2012

Balam-Ortiz Eros, Esquivel-Villarreal Adolfo, Huerta-Hernandez David, Fernandez-Lopez Juan Carlos, Alfaro-Ruiz Luis, Muñoz-Monroy Omar, Gutierrez Ruth, Figueroa-Genis Enrique, Carrillo Karol, Elizalde Adela, Hidalgo Alfredo, Rodriguez Mauricio, Urushihara Maki, Kobori Hiroyuki, Jimenez-Sanchez Gerardo

Abstract excerpt

The angiotensinogen gene locus has been associated with essential hypertension in most populations analyzed to date. Increased plasma angiotensinogen levels have been proposed as an underlying cause of essential hypertension in whites; however, differences in the genetic regulation of plasma angiotensinogen levels have also been reported for other populations. The aim of this study was to analyze the relationship...

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Identifiers

PMID: 22371359
DOI: 10.1161/HYPERTENSIONAHA.111.176453
PMCID: PMC3306465

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Source receipt: pubmed, retrieved 7 Sept 2026.

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