Article
Temporal temperature gradient electrophoresis for detection of single nucleotide polymorphisms.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2009
Jones Bethan M, Knapp Leslie A
Abstract excerpt
The presence of single nucleotide polymorphisms (SNPs) in nuclear DNA and mitochondrial DNA (mtDNA) can be detected using a range of electrophoretic techniques, of which temporal temperature gradient electrophoresis (TTGE) is often the most user-friendly and reproducible. The technique operates on the same principle as denaturing gradient gel electrophoresis, but does not require a chemical gradient in the gel....
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