Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of mitochondrial DNA mutations by temporal temperature gradient gel electrophoresis.

Clinical chemistry - 1 Aug 1999

Chen T J, Boles R G, Wong L J

Abstract excerpt

BACKGROUND: A unique requirement for the molecular diagnosis of mitochondrial DNA (mtDNA) disorders is the ability to detect heteroplasmic mtDNA mutations and to distinguish them from homoplasmic sequence variations before further testing (e.g., sequencing) is performed. We evaluated the potentia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to DNA, Mitochondrial
Share to Electrophoresis, Polyacrylamide Gel

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Point Mutation

Share to Polymerase Chain Reaction

Share to Polymorphism, Restriction Fragment Length

Share to Sequence Deletion

Share to Temperature

Source

Identifiers

PMID: 10430780

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-10430780-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of mitochondrial DNA mutations by temporal temperature gradient gel electrophoresis.PMID 10430780Read ↗

Detection of mitochondrial DNA mutations using temporal temperature gradient gel electrophoresis.Semantic proximity Read ↗

Comprehensive scanning of the entire mitochondrial genome for mutations.Semantic proximity Read ↗

Temporal temperature gradient electrophoresis for detection of single nucleotide polymorphisms.Semantic proximity Read ↗

Comprehensive molecular diagnosis of mitochondrial disorders: qualitative and quantitative approach.Semantic proximity Read ↗

Rapid detection of beta-globin gene mutations and polymorphisms by temporal temperature gradient gel electrophoresis.Semantic proximity Read ↗

Denaturing gradient gel method for mapping single base changes in human mitochondrial DNA.Semantic proximity Read ↗

Cycling temperature capillary electrophoresis: A quantitative, fast and inexpensive method to detect mutations in mixed populations of human mitochondrial DNA.Semantic proximity Read ↗

Scanning the mitochondrial genome for mutations by cycling temperature capillary electrophoresis.Semantic proximity Read ↗

Mutation screening of the TP53 gene by temporal temperature gradient gel electrophoresis.Semantic proximity Read ↗

Detecting mitochondrial genotypes by temperature gradient gel electrophoresis and heteroduplex analysis.Semantic proximity Read ↗

Quantitative mitochondrial DNA mutation analysis by denaturing HPLC.Semantic proximity Read ↗

Detection of CFTR mutations using temporal temperature gradient gel electrophoresis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.