Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Convergent extension movements in growth plate chondrocytes require gpi-anchored cell surface proteins.

Development (Cambridge, England) - 1 Oct 2009

Ahrens Molly J, Li Yuwei, Jiang Hongmei, Dudley Andrew T

Abstract excerpt

Proteins that are localized to the cell surface via glycosylphosphatidylinositol (gpi) anchors have been proposed to regulate cell signaling and cell adhesion events involved in tissue patterning. Conditional deletion of Piga, which encodes the catalytic subunit of an essential enzyme in the gpi-biosynthetic pathway, in the lateral plate mesoderm results in normally patterned limbs that display chondrodysplasia....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Proliferation
Share to Body Patterning
Share to Cell Polarity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chondrocytes

Share to Extremities

Share to Glycosylphosphatidylinositols

Share to Growth Plate

Share to Osteochondrodysplasias

Source

Open in PubMed Open full text

Identifiers

PMID: 19762422
DOI: 10.1242/dev.040592
PMCID: PMC2752396

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Convergent extension movements in growth plate chondrocytes require gpi-anchored cell surface proteins.PMID 19762422Read ↗

Genetic Dissection of the role of <i>Piga</i> and <i>Pgap2</i> in the embryonic mouse brainSemantic proximity Read ↗

Glycosylphosphatidylinositol Biosynthesis and Remodeling are Required for Neural Crest Cell, Cardiac and Neural DevelopmentSemantic proximity Read ↗

Understanding the Cellular and Molecular Mechanisms That Control Early Cell Fate Decisions During Appendicular SkeletogenesisSemantic proximity Read ↗

Development of the mammalian axial skeleton requires signaling through the Gα(i) subfamily of heterotrimeric G proteins.Semantic proximity Read ↗

Trophoblast differentiation defect in human embryonic stem cells lacking PIG-A and GPI-anchored cell-surface proteins.Semantic proximity Read ↗

Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors.Semantic proximity Read ↗

Role of glypican 4 in the regulation of convergent extension movements during gastrulation in Xenopus laevis.Semantic proximity Read ↗

The contribution of in vivo manipulation of gene expression to the understanding of the function of glypicans.Semantic proximity Read ↗

Rapid compensation for glycosylphosphatidylinositol anchor deficient keratinocytes after birth: visualization of glycosylphosphatidylinositol-anchored proteins in situ.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.