Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The contribution of in vivo manipulation of gene expression to the understanding of the function of glypicans.

Glycoconjugate journal - 1 Jan 2000

Filmus Jorge

Abstract excerpt

The name glypican identifies a family of heparan sulfate proteoglycans that are linked to the cell surface by a glycosylphosphatidylinositol anchor. Members of this family have been identified in Drosophila, zebrafish, and mammals. The interest in the study of glypicans has increased in the last...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drosophila
Share to Glypicans
Share to Growth Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Heparan Sulfate Proteoglycans

Share to Mammals

Share to Neoplasm Proteins

Share to Syndrome

Share to Zebrafish

Source

Identifiers

PMID: 12975611
DOI: 10.1023/A:1025312819804

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12975611-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The contribution of in vivo manipulation of gene expression to the understanding of the function of glypicans.PMID 12975611Read ↗

Fine-tuning of cell signaling by glypicans.Semantic proximity Read ↗

Alterations in mandibular morphology associated with glypican 1 and glypican 3 gene mutations.Semantic proximity Read ↗

Simpson Golabi Behmel syndrome: progress toward understanding the molecular basis for overgrowth, malformation, and cancer predisposition.Semantic proximity Read ↗

Glypican-3-deficient mice exhibit developmental overgrowth and some of the abnormalities typical of Simpson-Golabi-Behmel syndrome.Semantic proximity Read ↗

Mutations in the heparan-sulfate proteoglycan glypican 6 (GPC6) impair endochondral ossification and cause recessive omodysplasia.Semantic proximity Read ↗

Craniofacial skeletal defects of adult zebrafish Glypican 4 (knypek) mutants.Semantic proximity Read ↗

Mutation of the galectin-3 glycan-binding domain (Lgals3-R200S) enhances cortical bone expansion in male mice and trabecular bone mass in female mice.Semantic proximity Read ↗

What Have We Learned from Glycosyltransferase Knockouts in Mice?Semantic proximity Read ↗

Mutation of the Galectin-3 Glycan Binding Domain ( <i>Lgals3</i> -R200S) Enhances Cortical Bone Expansion in Male and Trabecular Bone Mass in Female MiceSemantic proximity Read ↗

Regulatory variation at glypican-3 underlies a major growth QTL in mice.Semantic proximity Read ↗

Altered hematopoiesis in glypican-3-deficient mice results in decreased osteoclast differentiation and a delay in endochondral ossification.Semantic proximity Read ↗

Gpc3 expression correlates with the phenotype of the Simpson-Golabi-Behmel syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.