Article
Processing and intracellular sorting of anglerfish and rat preprosomatostatins in mammalian endocrine cells.
Metabolism: clinical and experimental - 1 Sept 1990
Sevarino K A, Ventimiglia R, Stork P
Abstract excerpt
Rat preprosomatostatin (rPPSS) is processed to two distinct end products in a tissue-specific manner. The analogous end products in anglerfish are derived from separate precursors, anglerfish preprosomatostatins-1 and -2 (a(1)PPSS and a(II)PPSS). This report reviews experiments demonstrating that in mammalian cells, the cell of expression, not precursor structure, determines the processing fate of the...
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