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Article

Cleavage of a hydrophilic C-terminal domain increases growth-inhibitory activity of oncostatin M.

Molecular and cellular biology - 1 May 1990

Linsley P S, Kallestad J, Ochs V, Neubauer M

Abstract excerpt

Oncostatin M is a polypeptide cytokine, produced by normal and malignant hematopoietic cells, that has several in vitro activities, including the ability to inhibit growth of cultured carcinoma cells. Here we present a structural and functional comparison of two oncostatin M-related proteins (Mr 36,000 and 32,000) secreted by COS cells transfected with oncostatin M cDNA. The smaller of these forms lacked a...

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Identifiers

PMID: 2325640
DOI: 10.1128/mcb.10.5.1882-1890.1990
PMCID: PMC360533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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