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Article

The role of the Ca2+ binding ligand Asn879 in the function of the plasma membrane Ca2+ pump.

Biochimica et biophysica acta - 1 Nov 2009

Rinaldi Débora E, Adamo Hugo P

Abstract excerpt

Asn879 in the transmembrane segment M6 of the plasma membrane Ca(2+) pump (PMCA human isoform 4xb) has been proposed to coordinate Ca(2+) at the transport site through its carboxylate. This idea agrees with the fact that this Asn is conserved in other Ca(2+)-ATPases but is replaced by Asp, Glu, and other residues in closely related 2P-type ATPases of different ionic specificity. Previous mutagenesis studies have...

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Identifiers

PMID: 19761757
DOI: 10.1016/j.bbamem.2009.09.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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