Article
Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses.
BMC bioinformatics - 17 Sept 2009
Wongseree Waranyu, Assawamakin Anunchai, Piroonratana Theera, Sinsomros Saravudh, Limwongse Chanin, Chaiyaratana Nachol
Abstract excerpt
BACKGROUND: Purely epistatic multi-locus interactions cannot generally be detected via single-locus analysis in case-control studies of complex diseases. Recently, many two-locus and multi-locus analysis techniques have been shown to be promising for the epistasis detection. However, exhaustive m...
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