Summarizing techniques that combine three non-parametric scores to detect disease-associated 2-way SNP-SNP interactions.

Abstract excerpt

Identifying susceptibility genes that influence complex diseases is extremely difficult because loci often influence the disease state through genetic interactions. Numerous approaches to detect disease-associated SNP-SNP interactions have been developed, but none consistently generates high-quality results under different disease scenarios. Using summarizing techniques to combine a number of existing methods may...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Polymorphism, Single Nucleotide
• Share to Principal Component Analysis