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Article

Maternal medication use, carriership of the ABCB1 3435C > T polymorphism and the risk of a child with cleft lip with or without cleft palate.

American journal of medical genetics. Part A - 1 Oct 2009

Bliek Bart J B, van Schaik Ron H N, van der Heiden Ilse P, Sayed-Tabatabaei Fakhredin A, van Duijn Cock M, Steegers Eric A P, Steegers-Theunissen Régine P M

Abstract excerpt

Gene-environment interactions in the periconceptional period play an increasing role in the pathogenesis of birth defects, including cleft lip and/or cleft palate (CL/P). The P-glycoprotein, encoded by the ABCB1 gene, is suggested to protect the developing embryo from medication and other xenobio...

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Source

Identifiers

PMID: 19760622
DOI: 10.1002/ajmg.a.33036

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19760622-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Maternal medication use, carriership of the ABCB1 3435C > T polymorphism and the risk of a child with cleft lip with or without cleft palate.PMID 19760622Read ↗

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