Article
Developmental pharmacogenetics: a general paradigm for application to neonatal pharmacology and toxicology.
Clinical pharmacology and therapeutics - 1 Dec 2009
Leeder J S
Abstract excerpt
Therapy in newborn infants presents unique challenges. The consequences of exposure of the fetus to medications and environmental contaminants in utero (following the mother's exposure to these) may present, in the newborn, as congenital malformations or adverse drug reactions or have unknown long-term consequences. Risk is not uniformly distributed across a population. Rather, pharmacogenomic principles assert...
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