Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

General maternal medication use, folic acid, the MDR1 C3435T polymorphism, and the risk of a child with a congenital heart defect.

American journal of obstetrics and gynecology - 1 Mar 2011

Obermann-Borst Sylvia A, Isaacs Aaron, Younes Zobia, van Schaik Ron H N, van der Heiden Ilse P, van Duyn Cornelia M, Steegers Eric A P, Steegers-Theunissen Régine P M

Abstract excerpt

OBJECTIVE: We sought to investigate maternal and child functional MDR1 C3435T polymorphism, periconception medication, folic acid use, and the risk of a congenital heart defect (CHD) in the offspring. STUDY DESIGN: MDR1 3435C>T genotyping was performed in 283 case triads (mother, father, child) a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter, Subfamily B
Share to ATP Binding Cassette Transporter, Subfamily B, Member 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drug-Related Side Effects and Adverse Reactions

Share to Folic Acid

Share to Heart Defects, Congenital

Share to Maternal Exposure

Share to Prenatal Exposure Delayed Effects

Share to Vitamin B Complex

Source

Identifiers

PMID: 21183151
DOI: 10.1016/j.ajog.2010.10.911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21183151-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

General maternal medication use, folic acid, the MDR1 C3435T polymorphism, and the risk of a child with a congenital heart defect.PMID 21183151Read ↗

Maternal medication use, carriership of the ABCB1 3435C > T polymorphism and the risk of a child with cleft lip with or without cleft palate.Semantic proximity Read ↗

Maternal medication use, fetal 3435 C>T polymorphism of the ABCB1 gene, and risk of isolated septal defects in a Han Chinese population.Semantic proximity Read ↗

Association of maternal methionine synthase reductase gene polymorphisms with the risk of congenital heart disease in offspring: a hospital-based case-control study.Semantic proximity Read ↗

Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han population.Semantic proximity Read ↗

Association of maternal folic acid supplementation and offspring MTRR gene polymorphism with congenital heart disease: a hospital-based case-control study in Han populationSemantic proximity Read ↗

Folic Acid and Selected Risk Factors for Fetal Heart Defects—Preliminary Study ResultsSemantic proximity Read ↗

Do multivitamin or folic acid supplements reduce the risk for congenital heart defects? Evidence and gapsSemantic proximity Read ↗

Association between Maternal Drug Use and Cytochrome P450 Genetic Polymorphisms and the Risk of Congenital Heart Defects in Offspring.Semantic proximity Read ↗

Maternal and infant genetic variants, maternal periconceptional use of selective serotonin reuptake inhibitors, and risk of congenital heart defects in offspring: population based study.Semantic proximity Read ↗

[Maternal MTR gene polymorphisms and their interactions with periconceptional folic acid supplementation in relation to offspring ventricular septal defects].Semantic proximity Read ↗

Association of periconceptional folate supplements and FOLR1 and FOLR2 gene polymorphisms with risk of congenital heart disease in offspring: A hospital-based case-control study.Semantic proximity Read ↗

Two MTHFR polymorphisms, maternal B-vitamin intake, and CHDs.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.