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Article

Increased risk for congenital heart defects in children carrying the ABCB1 Gene C3435T polymorphism and maternal periconceptional toxicants exposure.

PloS one - 1 Jan 2013

Wang Chuan, Xie Liang, Zhou Kaiyu, Zhan Yalan, Li Yifei, Li Huaying, Qiao Lina, Wang Fang, Hua Yimin

Abstract excerpt

BACKGROUNDS: The etiology of congenital heart defect (CHD) is commonly believed to involve the interaction of multiple environmental and genetic factors. This study aimed to explore the joint effects of the ABCB1 gene C3435T polymorphism and maternal periconceptional toxicants exposure on the CHD risk in a Han Chinese population. METHODS: An age and gender matched case-control study with standardized data...

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Source

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Identifiers

PMID: 23874772
DOI: 10.1371/journal.pone.0068807
PMCID: PMC3714281

Genes

ABCB1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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