Article
Phosphorylation modulates rapid nucleocytoplasmic shuttling and cytoplasmic accumulation of Neurospora clock protein FRQ on a circadian time scale.
Genes & development - 15 Sept 2009
Diernfellner Axel C R, Querfurth Christina, Salazar Carlos, Höfer Thomas, Brunner Michael
Abstract excerpt
The Neurospora clock protein FREQUENCY (FRQ) is an essential regulator of the circadian transcription factor WHITE COLLAR COMPLEX (WCC). In the course of a circadian period, the subcellular distribution of FRQ shifts from mainly nuclear to mainly cytosolic. This shift is crucial for coordinating...
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