Core clock protein subcellular dynamics coordinate local and global circadian control in syncytia.

Abstract excerpt

Circadian rhythms are pervasive among eukaryotes, and the underlying clocks share a common regulatory architecture-a negative feedback loop. A wealth of genetic and biochemical data underpin current perceptions of circadian oscillators but aspects of their cell biology remain cryptic, especially in syncytial systems like Neurospora crassa. We employed novel microfluidic systems and a light-blind mutant that...

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