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[Association of IVS10+12G>A polymorphism in hMSH2 gene with colorectal cancer in Chinese].

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Oct 2010

Zhou Jian-nong, Wang De-qiang, Song Lei, Li Su-ping, Ding Jian-hua, Ma Guo-jian, Chen Sen-qing, Zhang Xiao-mei

Abstract excerpt

OBJECTIVE: To investigate the association of the single-nucleotide polymorphism (SNP) IVS10+12 G>A in hMSH2 gene with colorectal cancer in a Chinese population of Jiangsu province. METHODS: A case-control study to investigate whether this SNP affects the risk of developing colorectal cancer was conducted. Subjects included 108 colorectal cancer patients and 180 healthy individuals. Peripheral white blood cell DNA...

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Identifiers

PMID: 20931542
DOI: 10.3760/cma.j.issn.1003-9406.2010.05.023

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