Article
HTR2A gene variation is involved in antidepressant treatment response.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology - 1 Jan 2010
Lucae Susanne, Ising Marcus, Horstmann Sonja, Baune Bernhard T, Arolt Volker, Müller-Myhsok Bertram, Holsboer Florian, Domschke Katharina
Abstract excerpt
Two serotonin 2A receptor (HTR2A) SNPs recently reported to be associated with antidepressant treatment response in STARD (rs7997012; rs1928040) were analyzed for association with treatment response in two independent Caucasian samples of patients with a Major Depressive Episode. In the combined sample (n=637) SNP rs7997012 was significantly associated with remission after five weeks providing first replicative...
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