Article
5HT1A and 5HT2A receptor genes in treatment response phenotypes in major depressive disorder.
International clinical psychopharmacology - 1 Jul 2010
Noro Magali, Antonijevic Irina, Forray Carlos, Kasper Siegfried, Kocabas Neslihan Aygun, Lecrubier Yves, Linotte Sylvie, Mendlewicz Julien, Montgomery Stuart, Snyder Lenore, Souery Daniel, Verbanck Paul, Zohar Joseph, Massat Isabelle
Abstract excerpt
The 5HT2A (5HTR2A) and 5HT1A receptor (5HTR1A) genes are plausible candidate genes for major depressive disorders. Two single nucleotide polymorphisms, the rs7997012 in 5HTR2A and the -1019C/G in 5HTR1A, were analyzed in 206 patients with Diagnostic and Statistical Manual of Mental Disorders, fourth edition major depressive disorder. Patients were retrospectively characterized for clinical response to...
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