Article
Genome-wide association study identifies candidate loci associated with postoperative fentanyl requirements after laparoscopic-assisted colectomy.
Pharmacogenomics - 1 Jan 2016
Mieda Tsutomu, Nishizawa Daisuke, Nakagawa Hideyuki, Tsujita Miki, Imanishi Hirokazu, Terao Kazuhisa, Yoshikawa Hiroaki, Itoh Kazushi, Amano Kojiro, Tashiro Jo, Ishii Toshimasa, Ariyama Jun, Yamaguchi Shigeki, Kasai Shinya, Hasegawa Junko, Ikeda Kazutaka, Kitamura Akira, Hayashida Masakazu
Abstract excerpt
AIMS: Opioids are widely used as effective analgesics, but opioid sensitivity is well known to vary widely among individuals and the underlying genetic factors are not fully understood, thus hampering efficient pain treatment. We explored the genetic factors that contribute to individual differences in opioid sensitivity by performing a genome-wide association study. METHODS: We conducted a multistage genome-wide...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.