Article
Activity and impulsive action are controlled by different genetic and environmental factors.
Genes, brain, and behavior - 1 Nov 2009
Loos M, van der Sluis S, Bochdanovits Z, van Zutphen I J, Pattij T, Stiedl O, Smit A B, Spijker S
Abstract excerpt
Both impulsivity in operant tasks and locomotor activity in a novel open field are known to predict the development of addiction-related behavior in rodents. In this study, we investigated to what extent impulsivity in the five-choice serial reaction time task and various measures of novelty exploration are controlled by shared genetic and environmental factors in 12 different inbred mouse strains. No genetic...
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