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Article

Neuregulin-3 in the mouse medial prefrontal cortex regulates impulsive action.

Biological psychiatry - 15 Oct 2014

Loos Maarten, Mueller Thomas, Gouwenberg Yvonne, Wijnands Ruud, van der Loo Rolinka J, Birchmeier Carmen, Smit August B, Spijker Sabine

Abstract excerpt

BACKGROUND: A deficit in impulse control is a prominent, heritable symptom in several psychiatric disorders, such as addiction, attention-deficit/hyperactivity disorder, and schizophrenia. Here, we aimed to identify genes regulating impulsivity, specifically of impulsive action, in mice. METHODS: Using the widely used 5-choice serial reaction time task, we measured impulsive action in 1) a panel of 41 BXD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24703509
DOI: 10.1016/j.biopsych.2014.02.011

Genes

NRG3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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