Article
Heritable variation in locomotion, reward sensitivity and impulsive behaviors in a genetically diverse inbred mouse panel.
Genes, brain, and behavior - 1 Nov 2021
Bailey Lauren S, Bagley Jared R, Dodd Rainy, Olson Ashley, Bolduc Mikayla, Philip Vivek M, Reinholdt Laura G, Sukoff Rizzo Stacey J, Tarantino Lisa, Gagnon Leona, Chesler Elissa J, Jentsch James David
Abstract excerpt
Drugs of abuse, including alcohol and stimulants like cocaine, produce effects that are subject to individual variability, and genetic variation accounts for at least a portion of those differences. Notably, research in both animal models and human subjects point toward reward sensitivity and impulsivity as being trait characteristics that predict relatively greater positive subjective responses to stimulant...
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