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Article

Behavioural and neurochemical abnormalities in mice lacking functional tachykinin-1 (NK1) receptors: a model of attention deficit hyperactivity disorder.

Neuropharmacology - 1 Dec 2009

Yan Ting C, Hunt Stephen P, Stanford S Clare

Abstract excerpt

In rodent behavioural screens, such as the forced swim or resident/intruder tests, the behaviour of mice that lack functional substance P-preferring, tachykinin-1 receptors ((NK1R) either through drug antagonism or gene ablation) mimics that of wildtype mice that have been treated with an antidepressant drug. All antidepressants modify the function of monoamine-releasing neurones in the brain. Our intention was...

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PMID: 19748515
DOI: 10.1016/j.neuropharm.2009.08.021

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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