Article
The Trace Amine 1 receptor knockout mouse: an animal model with relevance to schizophrenia.
Genes, brain, and behavior - 1 Oct 2007
Wolinsky T D, Swanson C J, Smith K E, Zhong H, Borowsky B, Seeman P, Branchek T, Gerald C P
Abstract excerpt
Trace amines have been implicated in a number of neuropsychiatric disorders including depression and schizophrenia. Although long known to modulate neurotransmission indirectly through the release of catecholamines, the identification of the Trace Amine 1 receptor (TA1) offers a mechanism by which trace amines can influence synaptic activity directly. TA1 binds and is activated by trace amines such as...
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