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Article

A lack of functional NK1 receptors explains most, but not all, abnormal behaviours of NK1R-/- mice(1).

Genes, brain, and behavior - 1 Feb 2015

Porter A J, Pillidge K, Tsai Y C, Dudley J A, Hunt S P, Peirson S N, Brown L A, Stanford S C

Abstract excerpt

Mice lacking functional neurokinin-1 receptors (NK1R-/-) display abnormal behaviours seen in Attention Deficit Hyperactivity Disorder (hyperactivity, impulsivity and inattentiveness). These abnormalities were evident when comparing the behaviour of separate (inbred: 'Hom') wildtype and NK1R-/- mouse strains. Here, we investigated whether the inbreeding protocol could influence their phenotype by comparing the...

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Identifiers

PMID: 25558794
DOI: 10.1111/gbb.12195
PMCID: PMC4415486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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