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Article

Age-dependent expression of hephaestin in the brain of ceruloplasmin-deficient mice.

Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) - 1 Jan 2009

Cui Rui, Duan Xiang-Lin, Anderson Gregory J, Qiao Ya-Tiao, Yu Peng, Qian Zhong-Ming, Yoshida Kunihiro, Takeda Shin'ichi, Guo Pei, Yang Zhen-Ling, Chang Yan-Zhong

Abstract excerpt

Aceruloplasminemia is an autosomal recessive disorder caused by mutations in the ceruloplasmin (CP) gene. It is characterized by iron accumulation in the brain and in visceral organs. However, little is known about the mechanism of iron transport in these regions. Adult CP null (CP(-/-)) mice show increased iron deposition in several regions of brain, such as the cerebellum and brainstem. In this study, we...

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Identifiers

PMID: 19747625
DOI: 10.1016/j.jtemb.2009.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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