Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of Na+/H+ and HCO3- -dependent transporters in Na+/H+ exchanger isoform 1 null mutant mouse brain.

Neuroscience - 1 Jan 2003

Xue J, Douglas R M, Zhou D, Lim J Y, Boron W F, Haddad G G

Abstract excerpt

Acid-base transporters, such as the sodium-hydrogen exchangers (NHEs) and bicarbonate-dependent transporters, play an important role in the regulation of intracellular pH (pH(i)) in the CNS. Previous studies from our laboratory have shown that the absence of the major NHE isoform 1 (NHE1) reduced the steady-state pH(i) and recovery rate from an acid load in the hippocampal neurons not only in HEPES but also in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain Stem
Share to Cation Transport Proteins
Share to Cerebellum

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Densitometry

Share to Hippocampus

Share to Immunoblotting

Share to Sodium-Bicarbonate Symporters

Share to Sodium-Hydrogen Exchangers

Source

Identifiers

PMID: 14596847
DOI: 10.1016/s0306-4522(03)00598-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of Na+/H+ and HCO3- -dependent transporters in Na+/H+ exchanger isoform 1 null mutant mouse brain.PMID 14596847Read ↗

Increased neuronal excitability and seizures in the Na(+)/H(+) exchanger null mutant mouse.Semantic proximity Read ↗

Two variants of the rat brain sodium-driven chloride bicarbonate exchanger (NCBE): developmental expression and addition of a PDZ motif.Semantic proximity Read ↗

Sodium/hydrogen exchanger gene defect in slow-wave epilepsy mutant mice.Semantic proximity Read ↗

Mouse models of SLC4-linked disorders of HCO3--transporter dysfunction.Semantic proximity Read ↗

Cloning, Characterization, and Chromosomal Mapping of a Human Electroneutral Na+-driven Cl-HCO3ExchangerSemantic proximity Read ↗

Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger.Semantic proximity Read ↗

Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability.Semantic proximity Read ↗

Acid-base effects of combined renal deletion of NBCe1-A and NBCe1-B.Semantic proximity Read ↗

An inducible intestinal epithelial cell-specific NHE3 knockout mouse model mimicking congenital sodium diarrhea.Semantic proximity Read ↗

Cloning, localization, and functional expression of the electrogenic Na+ bicarbonate cotransporter (NBCe1) from zebrafish.Semantic proximity Read ↗

Alkaline-shifted pHo sensitivity of AE2c1-mediated anion exchange reveals novel regulatory determinants in the AE2 N-terminal cytoplasmic domain.Semantic proximity Read ↗

Resistance to cardiomyocyte hypertrophy in ae3-/- mice, deficient in the AE3 Cl-/HCO3- exchanger.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.