Article
Mechanistic insights in light-induced cAMP production by photoactivated adenylyl cyclase alpha (PACalpha).
Biological chemistry - 1 Nov 2009
Looser Jens, Schröder-Lang Saskia, Hegemann Peter, Nagel Georg
Abstract excerpt
The flagellate Euglena gracilis contains as photoreceptor complex a heterotetrameric light-sensitive adenylyl cyclase (AC), consisting of the flavoproteins PACalpha and PACbeta. Previously, we demonstrated the functional expression of PACalpha and PACbeta in oocytes from Xenopus laevis and of PACalpha in different animal cell types. Both yielded a blue light-induced increase of cellular [cAMP]. Here, we report...
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