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Article

Regulation of MYPT1 stability by the E3 ubiquitin ligase SIAH2.

Experimental cell research - 1 Jan 2010

Twomey Erin, Li Yan, Lei Joy, Sodja Caroline, Ribecco-Lutkiewicz Maria, Smith Brandon, Fang Hung, Bani-Yaghoub Mahmud, McKinnell Iain, Sikorska Marianna

Abstract excerpt

Myosin phosphatase target subunit 1 (MYPT1), together with catalytic subunit of type1 delta isoform (PP1cdelta) and a small 20-kDa regulatory unit (M20), form a heterotrimeric holoenzyme, myosin phosphatase (MP), which is responsible for regulating the extent of myosin light chain phosphorylation...

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Source

Identifiers

PMID: 19744480
DOI: 10.1016/j.yexcr.2009.09.001

Genes

SIAH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19744480-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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