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Article

Maintenance of type 2 glycolytic myofibers with age by Mib1-Actn3 axis.

Nature communications - 26 Feb 2021

Seo Ji-Yun, Kang Jong-Seol, Kim Ye Lynne, Jo Young-Woo, Kim Ji-Hoon, Hann Sang-Hyeon, Park Jieon, Park Inkuk, Park Hyerim, Yoo Kyusang, Rhee Joonwoo, Park Jung-Wee, Ha Yong Chan, Kong Young-Yun

Abstract excerpt

Age-associated muscle atrophy is a debilitating condition associated with loss of muscle mass and function with age that contributes to limitation of mobility and locomotion. However, the underlying mechanisms of how intrinsic muscle changes with age are largely unknown. Here we report that, with age, Mind bomb-1 (Mib1) plays important role in skeletal muscle maintenance via proteasomal degradation-dependent...

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Identifiers

PMID: 33637766
DOI: 10.1038/s41467-021-21621-6
PMCID: PMC7910585

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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