Article
Protein arginine methyltransferase expression, localization, and activity during disuse-induced skeletal muscle plasticity.
American journal of physiology. Cell physiology - 1 Feb 2018
Stouth Derek W, Manta Alexander, Ljubicic Vladimir
Abstract excerpt
Protein arginine methyltransferase 1 (PRMT1), PRMT4, and PRMT5 catalyze the methylation of arginine residues on target proteins. Previous work suggests that these enzymes regulate skeletal muscle plasticity. However, the function of PRMTs during disuse-induced muscle remodeling is unknown. The purpose of our study was to determine whether denervation-induced muscle disuse alters PRMT expression and activity in...
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