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Article

Novel rare alleles of ABCA1 are exclusively associated with extreme high-density lipoprotein-cholesterol levels among the Han Chinese.

Clinical chemistry and laboratory medicine - 1 Jan 2009

Hu Suwei, Zhong Yanfang, Hao Yuantao, Luo Minqi, Zhou Yan, Guo Hui, Liao Weijiao, Wan Desheng, Wei Haiyun, Gao Yueting, Shan Jinglan, Hu Bin, Hultén Maj, Wang Yiming

Abstract excerpt

BACKGROUND: High-density lipoprotein (HDL) is a major plasma lipoprotein directly associated with cholesterol metabolism. The ATP binding cassette transporter 1 gene (ABCA1) is one of the major genes modulating plasma levels of HDL-cholesterol (HDL-C). Rare alleles of ABCA1 associated with extreme HDL-C concentrations have not been previously investigated in the Chinese. METHODS: Blood samples were collected from...

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Identifiers

PMID: 19743957
DOI: 10.1515/CCLM.2009.284

Genes

ABCA1

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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