Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variations on a gene: rare and common variants in ABCA1 and their impact on HDL cholesterol levels and atherosclerosis.

Annual review of nutrition - 1 Jan 2006

Brunham Liam R, Singaraja Roshni R, Hayden Michael R

Abstract excerpt

Cholesterol and its metabolites play a variety of essential roles in living systems. Virtually all animal cells require cholesterol, which they acquire through synthesis or uptake, but only the liver can degrade cholesterol. The ABCA1 gene product regulates the rate-controlling step in the removal of cellular cholesterol: the efflux of cellular cholesterol and phospholipids to an apolipoprotein acceptor....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atherosclerosis
Share to ATP Binding Cassette Transporter 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to ATP-Binding Cassette Transporters

Share to Cholesterol

Share to Cholesterol, HDL

Share to ABCA1 gene

Share to Genetic Variation

Share to Mutation

Source

Identifiers

PMID: 16704350
DOI: 10.1146/annurev.nutr.26.061505.111214

Genes

ABCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variations on a gene: rare and common variants in ABCA1 and their impact on HDL cholesterol levels and atherosclerosis.PMID 16704350Read ↗

The Role of the ATP-Binding Cassette A1 (ABCA1) in Human Disease.Semantic proximity Read ↗

Efflux and atherosclerosis: the clinical and biochemical impact of variations in the ABCA1 gene.Semantic proximity Read ↗

Common and rare ABCA1 variants affecting plasma HDL cholesterol.Semantic proximity Read ↗

Common genetic variation in ABCA1 is associated with altered lipoprotein levels and a modified risk for coronary artery disease.Semantic proximity Read ↗

Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general population.Semantic proximity Read ↗

Genetic disorders associated with ATP binding cassette cholesterol transporters.Semantic proximity Read ↗

Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general populationSemantic proximity Read ↗

Genetic variation in the ABCA1 gene, HDL cholesterol, and risk of ischemic heart disease in the general population.Semantic proximity Read ↗

Genotypic variation in ATP-binding cassette transporter-1 (ABCA1) as contributors to the high and low high-density lipoprotein-cholesterol (HDL-C) phenotype.Semantic proximity Read ↗

Novel rare mutations and promoter haplotypes in ABCA1 contribute to low-HDL-C levels.Semantic proximity Read ↗

Effect of two common polymorphisms in the ATP binding cassette transporter A1 gene on HDL-cholesterol concentration.Semantic proximity Read ↗

High-density single-nucleotide polymorphism (SNP) map of the 150-kb region corresponding to the human ATP-binding cassette transporter A1 (ABCA1) gene.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.