ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels.

doi:10.1161/ATVBAHA.117.309574

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Article

ABCA8 Regulates Cholesterol Efflux and High-Density Lipoprotein Cholesterol Levels.

Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2017

Trigueros-Motos Laia, van Capelleveen Julian C, Torta Federico, Castaño David, Zhang Lin-Hua, Chai Ee Chu, Kang Martin, Dimova Lidiya G, Schimmel Alinda W M, Tietjen Ian, Radomski Chris, Tan Liang Juin, Thiam Chung Hwee, Narayanaswamy Pradeep, Wu Daniel Heqing, Dorninger Fabian, Yakala Gopala Krishna, Barhdadi Amina, Angeli Veronique, Dubé Marie-Pierre, Berger Johannes, Dallinga-Thie Geesje M, Tietge Uwe J F, Wenk Markus R, Hayden Michael R, Hovingh G Kees, Singaraja Roshni R

Abstract excerpt

OBJECTIVE: High-density lipoproteins (HDL) are considered to protect against atherosclerosis in part by facilitating the removal of cholesterol from peripheral tissues. However, factors regulating lipid efflux are incompletely understood. We previously identified a variant in adenosine triphosphate-binding cassette transporter A8 (ABCA8) in an individual with low HDL cholesterol (HDLc). Here, we investigate the...

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PMID: 28882873
DOI: 10.1161/ATVBAHA.117.309574

Genes

ABCA8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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