Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Administration of a mutated myostatin propeptide to neonatal mice significantly enhances skeletal muscle growth.

Molecular reproduction and development - 1 Jan 2010

Li Zicong, Zhao Baoping, Kim Yong Soo, Hu Ching Yuan, Yang Jinzeng

Abstract excerpt

Myostatin is a dominant inhibitor of skeletal muscle development and growth. As transgenic over-expression of myostatin propeptide dramatically enhanced muscle mass, we hypothesized that administration of myostatin propeptide will increase muscle growth. In this study, the wild-type form of porcine myostatin propeptide and its mutated form at the cleavage site of metalloproteinases of BMP-1/TLD family were...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Muscle, Skeletal
Share to Animals, Newborn

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Line

Share to Insecta

Share to Myostatin

Share to Protein Precursors

Source

Identifiers

PMID: 19743472
DOI: 10.1002/mrd.21111

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Administration of a mutated myostatin propeptide to neonatal mice significantly enhances skeletal muscle growth.PMID 19743472Read ↗

Functional verification of a porcine myostatin propeptide mutant.Semantic proximity Read ↗

Over-Expression of Porcine Myostatin Missense Mutant Leads to A Gender Difference in Skeletal Muscle Growth between Transgenic Male and Female Mice.Semantic proximity Read ↗

INVITED REVIEW: Inhibitors of myostatin as methods of enhancing muscle growth and development.Semantic proximity Read ↗

Mutation in myostatin 3'UTR promotes C2C12 myoblast proliferation and differentiation by blocking the translation of MSTN.Semantic proximity Read ↗

The myostatin gene: an overview of mechanisms of action and its relevance to livestock animals.Semantic proximity Read ↗

Myostatin site-directed mutation and simultaneous PPARγ site-directed knockin in bovine genome.Semantic proximity Read ↗

Myostatin's marvels: From muscle regulator to diverse implications in health and diseaseSemantic proximity Read ↗

A <i>MSTN</i> <sup>Del273C</sup> mutation with <i>FGF5</i> knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasiaSemantic proximity Read ↗

Long-term enhancement of skeletal muscle mass and strength by single gene administration of myostatin inhibitorsSemantic proximity Read ↗

Targeted mutations in myostatin by zinc-finger nucleases result in double-muscled phenotype in Meishan pigs.Semantic proximity Read ↗

A MSTNDel73C mutation with FGF5 knockout sheep by CRISPR/Cas9 promotes skeletal muscle myofiber hyperplasiaSemantic proximity Read ↗

Generation of heritable double muscle buttocks rabbits via myostatin mutation with CRISPR/Cas9 systemSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.