Article
DNA polymorphism of major histocompatibility complex class II and class III genes in systemic lupus erythematosus.
Tissue antigens - 1 Mar 1990
So A K, Fielder A H, Warner C A, Isenberg D A, Batchelor J R, Walport M J
Abstract excerpt
We investigated the Taq I digested DNA restriction fragment length polymorphism (RFLP) of the Major Histocompatibility Complex (MHC) class II genes: HLA-DRB, -DQA, and the class III genes: C4 and 21-hydroxylase(CYP21) in 56 caucasoid patients with systemic lupus erythematosus (SLE) and 62 control...
Topics
- Complement C4
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DR Antigens
- Humans
- Lupus Erythematosus, Systemic
- Major Histocompatibility Complex
- Polymorphism, Restriction Fragment Length
- Steroid 21-Hydroxylase