Article
Major histocompatibility complex class II and C4 alleles in Mexican Americans with systemic lupus erythematosus.
Tissue antigens - 1 Feb 1995
Reveille J D, Moulds J M, Arnett F C
Abstract excerpt
Few data exist on associations of class II and class III alleles of the major histocompatibility complex (MHC) and susceptibility to systemic lupus erythematosus (SLE) in Mexican Americans, a group of predominantly mixed Spanish and Native American ancestry. Therefore, MHC class II alleles (HLA-DRB1, DQA1, DQB1, DPA1 and DPB1 alleles) and C4 allotypes were determined in 52 Mexican American SLE patients and 105...
Topics
- Alleles
- Autoantibodies
- Base Sequence
- Complement C4
- Disease Susceptibility
- Gene Frequency
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-D Antigens
- Haplotypes
- Humans