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Article

A rare complement component C4 restriction fragment length polymorphism in two families with systemic lupus erythematosus.

The Journal of rheumatology - 1 Mar 1991

Goldstein R, Moulds J M, Sengar D P

Abstract excerpt

C4 null alleles with or without C4A,21-OHA gene deletions are associated with systemic lupus erythematosus (SLE) in various populations. We describe a new, rare C4 restriction fragment length polymorphism (RFLP), a Taq I 3.5 kb fragment, in 2 patients with SLE and their families. This RFLP is not...

Topics

Adult
Alleles
Blotting, Southern
Chromosome Deletion
Complement C4
Complement C4b
Female
Haplotypes
Humans
Lupus Erythematosus, Systemic
Major Histocompatibility Complex
Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Peptide Fragments

Polymorphism, Genetic

Polymorphism, Restriction Fragment Length

Source

Identifiers

PMID: 1677422

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1677422-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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