Article
A rare complement component C4 restriction fragment length polymorphism in two families with systemic lupus erythematosus.
The Journal of rheumatology - 1 Mar 1991
Goldstein R, Moulds J M, Sengar D P
Abstract excerpt
C4 null alleles with or without C4A,21-OHA gene deletions are associated with systemic lupus erythematosus (SLE) in various populations. We describe a new, rare C4 restriction fragment length polymorphism (RFLP), a Taq I 3.5 kb fragment, in 2 patients with SLE and their families. This RFLP is not associated with one particular major histocompatibility complex (MHC) haplotype and has not been reported in patients...
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