Article
Molecular analysis of major histocompatibility complex allelic associations with systemic lupus erythematosus in Taiwan.
Arthritis and rheumatism - 1 Jun 1997
Lu L Y, Ding W Z, Fici D, Deulofeut R, Cheng H H, Cheu C C, Sung P K, Schur P H, Fraser P A
Abstract excerpt
OBJECTIVE: To investigate the association of HLA class II alleles/haplotypes, type I C2 deficiency gene, and tumor necrosis factor a gene promoter allele (TNF2) with systemic lupus erythematosus (SLE) in the Chinese population in Taiwan. METHODS: The HLA-DRB1 and DQB1 alleles were studied in 105 SLE patients and 115 controls by the polymerase chain reaction (PCR)/sequence-specific oligonucleotide probe method,...
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