Article
A risk variant in an miR-125b binding site in BMPR1B is associated with breast cancer pathogenesis.
Cancer research - 15 Sept 2009
Saetrom Pål, Biesinger Jacob, Li Sierra M, Smith David, Thomas Laurent F, Majzoub Karim, Rivas Guillermo E, Alluin Jessica, Rossi John J, Krontiris Theodore G, Weitzel Jeffrey, Daly Mary B, Benson Al B, Kirkwood John M, O'Dwyer Peter J, Sutphen Rebecca, Stewart James A, Johnson David, Larson Garrett P
Abstract excerpt
MicroRNAs regulate diverse cellular processes and play an integral role in cancer pathogenesis. Genomic variation within miRNA target sites may therefore be important sources for genetic differences in cancer risk. To investigate this possibility, we mapped HapMap single nucleotide polymorphisms...
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