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BMPR1B Polymorphisms (rs1434536 and rs1970801) are Associated With Breast Cancer Susceptibility in Northwest Chinese Han Females: A Case-Control Study.

Clinical breast cancer - 1 Jul 2022

Zheng Yi, Jiang Xun, Wang Meng, Yang Si, Deng Yujiao, Li Yizhen, Zhai Zhen, Wu Ying, Wang Nan, Ren Xueting, Kang Huafeng, Chen Lei

Abstract excerpt

BACKGROUND: Bone morphogenetic proteins receptor type 1B (BMPR1B) was a multifunctional signaling molecule and its abnormal expression associated with poorer prognosis. We aimed to explore the relationship between BMPR1B polymorphisms and breast cancer susceptibility among northwest population. METHODS: A total of 450 healthy controls and 434 patients with breast cancers were recruited in this study. Two...

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PMID: 35501253
DOI: 10.1016/j.clbc.2022.02.011

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