Article
Redox characterization of human cyclophilin D: identification of a new mammalian mitochondrial redox sensor?
Archives of biochemistry and biophysics - 1 Nov 2009
Linard Dominique, Kandlbinder Andrea, Degand Hervé, Morsomme Pierre, Dietz Karl-Josef, Knoops Bernard
Abstract excerpt
Mitochondria are metabolically highly active cell organelles that are also implicated in reactive oxygen species production and in cell death regulation. Cyclophilin D, the only human mitochondrial isoform of cyclophilins, plays an essential role in the formation of the mitochondrial permeability...
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